Causes of Type II Diabetes
Diabetes Mellitus is a disease in which a patient suffers from high blood sugar levels. High sugar levels are a direct result of low or no production of insulin in the pancreas. Insulin is a hormone produced by pancreas and is responsible for maintenance of glucose levels in the blood. With low or no production of insulin from the pancreas, the body cannot correctly store and use sugar and carbohydrates from ingested foods. One other cause for Diabetes is that while the pancreas is producing insulin and in the correct amounts, the cells of the body are reacting incorrectly to the insulin and thus the sugars aren’t correctly processed.
Type II Diabetes was previously more commonly known as “insulin resistant diabetes” or “non-insulin dependent diabetes”. Type II Diabetes is the most common of the three types accounting for approximately 90% of all diabetic diagnosis. Symptoms of Type II Diabetes are very similar to that of Type I Diabetes but are less pronounced and may not show for years.
Type II Diabetes could occur due to following causes:
Insulin abnormality such as insulin resistance, excessive insulin production or sudden fall in insulin production could lead to Diabetes Type II. There are speculations that calpains proteins may affect insulin secretion and insulin action. Abnormal regulation of some important peptides may lead to changes in blood circulation. This may also cause insulin resistance. High levels of free fatty acids and the hormones are also considered as a triggering factor for insulin resistance.
Type II Diabetes may occur due to certain genetic factors. A patient with a family history of Type II Diabetes is more prone to develop Type II Diabetes. Studies have suggested that there are several genes, which are responsible for development of Type II Diabetes.
People with certain ethnic origins are at higher risk of developing Type II Diabetes. Patients with African American, Native American, Hispanic American, and Japanese American origins are at higher risk of developing Type II Diabetes. The risk increases if they have any close relative suffering from Type II Diabetes or Gestational Diabetes.
Elderly patients are more likely to develop Type II Diabetes. Increasing age elevates the risk factor for Type II Diabetes. Patients above age of 45 years have slightly higher risk and patients above age of 65 years have significant risk of developing Type II Diabetes.
Other factors, which may lead to Type II Diabetes are high level of triglyceride or fat in blood, high blood pressure, high alcohol intake or high fat intake by the patient, obesity, gestational diabetes or giving birth to a heavy weight baby. Increased glucose production in the liver may also lead to Type II Diabetes. Increased fat breakdown and defective hormonal secretions in the intestine may also trigger this type of diabetes. Inactivity or sedentary lifestyle is also responsible for development of Type II Diabetes.