• The Generic Name is :- Metoclopramide
  • The Brand Name is: – Metoclopramide, Reglan, Reglan ODT, Metozol ODT, Octamide.

Maxolon was another brand name that has now been discontinued.

Drug Functionality:

Reglan or metoclopromide is a “prokinetic” medicine that stimulates the muscles of gastrointestinal tract. In other words, when this medicine is injected into the system, it increases the contractions of stomach and intestines. This helps to diagnose problems related to any of the before mentioned organs. It is mainly meant to treat people suffering from heartburn due to gastroesophageal reflux.

It is essentially prescribed in cases where other treatments have either failed or have provided little relief. The side effects of Reglan are serious and can linger even after the medication is stopped, so, this drug should be taken only under medical supervision and not for more than 4- 12 weeks.

Heartburn that mainly occurs after a meal or during the daytime is because of the fact that the reflux of acid and other contents in the stomach are allowed to back up in the esophagus (throat in layman terms) by the weak lower esophageal sphincter. Hence the food is being pumped back in to the esophagus or the food pipe, causing heartburn. Reglan, without disturbing the gastric, biliary, or pancreatic secretions, stimulates the motility of the upper gastrointestinal tract and stomach, thereby emptying the solid and liquid meals from the stomach into the intestines. This way it treats the heartburn and also prevents the symptoms of nausea, vomiting and stomach/abdominal fullness.

Forms of Reglan: Reglan as a drug is available in the following forms:

  1. Syrup
  2. Solutions
  3. Disintegrating tablets
  4. Tablets

Syrups and solutions are colorless and odorless and should be discarded if a particulate is observed in the medicine. Disintegrating tablet should be removed from the blister pack only at the time of taking the medicine. It should be directly placed into the mouth, and should be allowed to dissolve with saliva. If in the process of taking the medicine, the medicine breaks or crumbles, the same should be discarded and a new tablet should be taken from the blister pack.

Dosage:

  • The dosage of Reglan is patient specific. So it is very important to take the dosage either as directed by the doctor or as prescribed on the label. Taking more than the prescribed dose can prove lethal as it has a serious side effect of involuntary movements of muscles.
  • Dosage also depends on the medical problem for which it has been prescribed. Other than this, the strength of the medicine, no of doses, time interval between doses and the duration of the medication play a vital role.

Uses:

  1. 1. For treating gastroparesis in diabetic patients, Reglan can be taken in the following manner
  • In oral dosage forms mainly for diabetic patients,
    • Adults and teenagers should take 10 milligrams before each meal and at bedtime. The dose can be taken up to four times a day.
    • Only pediatricians can prescribe this medication for children
  1. For treating GERD i.e. Gastro-Esophageal Reflux Disease
  • In oral dosage forms
    • Adults and teenagers should take 10 to 15 milligrams at least half an hour before symptoms appear, or before meal times and at bed time. The dose can be taken up to four times a day or as prescribed by the doctor.
    • Only pediatricians can prescribe this medication for children

Precautions:

  1. Before your doctor prescribes Reglan, do mention all the medications (herbal, allopathic or any other), that you are taking.
  2. In case one is suffering from any of the mentioned ailments, Reglan should be taken only after discussion with the registered practitioner.
  • Gastrointestinal bleeding or perforation
  • A gastrointestinal blockage
  • Pheochromocytoma
  • Seizures or epilepsy
  • Depression or a history of depression
  • Parkinson’s disease
  • Heart failure
  • Liver failure
  • Any other allergies, including allergies to food, dyes, or preservatives.
  1. If you are breastfeeding, pregnant or planning pregnancy, the same should be discussed with the doctor. Though Reglan has not reported any major repercussion to the unborn baby, however it should be prescribed only if the doctor feels that the benefits to the pregnant woman will outweigh the risk. Also, it has been seen that if the medicine is passed to the nursing baby through breast milk, it may prove fatal. Hence as mentioned before as well, this medicine should be taken only under medical supervision.