is an anticoagulant drug. It contains Dabigatran as its main active ingredient. It belongs to an anticoagulant group of drugs called direct thrombin inhibitor. It prevents clotting in the blood. It is used as blood thinner in patients who have clot problems or risk of blood clotting. It is Dabigatran etexilate mesylate, which is a yellow- white powder. It is freely soluble in methanol, slightly soluble in ethanol and isopropanol. It is soluble in water. It has acacia, dimethicone, hypromellose, hydroxypropyl cellulose, talc, and tartaric acid as inactive ingredients. It is manufactured by Boehringer Ingelheim Pharmaceuticals, Inc.

Uses of Pradaxa

It is prescribed to patients of heart disorder for prevention of blood clots and hence reducing the risk of stroke. Pradaxa reduces the risk of developing blood clots in the patient’s body.  Sometimes these clots break free from their point of origin and circulated with the blood and can even move to a blood vessel of the brain, and block blood flow to the . Due to this strokes are caused. By preventing clots Pradaxa lowers risk of stroke in the patient.

It is used as blood thinners in patients who have higher risk of blood clotting. Blood clots could travel to heart or lungs and could cause serious complications. Thus by preventing blood clots or thinning blood this drug reduces risk of some serious health complications. It is a direct thrombin inhibitor. It acts by blocking production of thrombin in the blood. Thrombin is responsible for clotting of blood thus use of Pradaxa lowers risk of blood clots.

Precautions Before Taking Pradaxa

  • Pradaxa should be stored at room temperature. It should be kept away from moisture and heat. It should not be left open, out of the pack.
  • Any Pradaxa capsule should not be taken from a bottle, which is open for more than 4 months.
  • Patients allergic with Dabigatran or any other ingredient of this drug should not use Pradaxa.
  • Patients should consult their doctor about any allergy or any medicine being taken before using this drug as it could cause serious medical complications by interacting with certain drugs.
  • Patients should avoid any activity, which involve risk of bleeding. Even a minor cut could be serious while using Pradaxa as it prevents clotting, bleeding may be continuous or non stoppable. In case of any injury while using this medicine immediately call your doctor.
  • Patients should tell their doctor before any surgery, dental work, or any type of medical test or treatment, if you are using Pradaxa as it may accentuate bleeding.
  • If a patient develops weakness, feeling like passing out, easy bruising, unusual bleeding from nose, mouth, vagina, or rectum, it is advisable to seek immediate medical help.
  • Purple or red spots under skin, changes in color of urine, bloody or tarry stools, bloody cough, joint pain or swelling are other alarming conditions while using this drug.
  • Patients should immediately consult their doctor if they have heavy menstrual bleeding, while using Pradaxa.
  • Pradaxa should not be used with any other blood-thinning drug, as it will increase the risk of unstoppable bleeding.
  • Patients with kidney disease or a history of stomach ulcer or bleeding should consult their doctor before using this medicine.
  • Patients who are over 75 years should first consult their doctor about using this medicine.
  • Pradaxa should not be used by pregnant patients or patients who are planning or suspecting pregnancy as its harmful effects on fetus are not fully known. It could harm the unborn child.
  • Nursing mothers should avoid this drug as it could harm the baby. It easily passes into the breast milk.
  • Patients should undergo regular screening of kidney function while using Pradaxa.
  • Its overdose could be fatal, thus patients should stick to recommended dosages. Overdose symptoms are excessive or unstoppable bleeding.
  • Patients with any bleeding problem in any part of the body or a bleeding disorder should not use Pradaxa or consult their doctor about its use.
  • Patients with any liver disease, recent major injury or surgery, infection in the heart or stroke should also consult the doctor before using Pradaxa.
  • Patients should avoid use of while using this medicine.