In a statement issued by Merck, one of the biggest pharmaceutical companies in U.S., it agreed to pay $321 million as criminal fine and plead guilty for illegally introduction of the drug in interstate commerce. As per the settlement case, the company will be paying a total of $950 million to different agencies. Vioxx was introduced as a pain killer and was approved by FDA in 1999. In 2002 Merck marketed the same drug as a treatment drug for rheumatoid arthritis.

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