Humira is an anti inflammation drug. It contains Adalimumab as main active ingredient. It belongs to recombinant human IgG1 monoclonal antibody group of drugs. It is specifically designed for human TNF or tumor necrosis factor. It acts by affecting substance responsible for inflammation in the body. It comes as a sterile injection along with a glass syringe. It is used to reduce inflammation in rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis, and plaque psoriasis. Other use of this drug is treatment of Crohn’s disease after other drugs fail to successfully treat it. It is manufactured by Abbott Laboratories.

Patients allergic to Adalimumab should not take this injection. Patients with tuberculosis or other infections should avoid this injection. Patients should consult the doctor about their allergies, medical history or medicines being used to avoid any harmful effect of this drug as it could worsen certain medical conditions or interact with certain drugs. Patients of TB, fungal infection such as histoplasmosis, congestive heart failure, lupus, recurrent infections, hepatitis B infection, decreased bone marrow function, seizures, brain or spinal cord disorders or history of cancer should consult doctor before taking this injection.

Elderly patients are more sensitive to the side effects of this drug, thus they should consult the doctor before having Humira injection. It should be avoided during pregnancy, suspected pregnancy or breast-feeding as its harmful effects to baby are not fully known yet. Patients should avoid vaccination or contact with vaccinated people, while having Humira injections.

It increases the risk of cancer such as lymphoma or autoimmune disorders. The risk is higher in children and young patients. Use of this medicine could lower white blood cell count and make it easy to bleed or catch an infection. Patients should undergo regular blood tests, while using this injection.

Use of Humira could increase risk of fatal infections. Patients should call doctor if they experience fever, sweating, chills, tiredness, shortness of breath, cough, sore throat, flu symptoms or weight loss. Some patients may also experience allergic reactions such as rashes, swelling of face, lips, throat or tongue or hives. Humira could also cause swelling of ankles or feet, confusion, pain or burning while urinating, seizure, chest pain, continuous or bloody cough, easy bruising or bleeding or unusual weakness as a side effect.

Other side effects associated with Humira injections are numbness, weakness in legs, jaundice, mouth sores, pale skin, red, purple or scaly rash on skin, hair loss, joint or muscle pain, swollen glands, vomiting, unusual thoughts or behavior, patchy skin, headache, pain in sinus or stuffed nose.  Some patients may also experience pain, swelling, itching or redness at place of injection. It could also cause fast, irregular or pounding heartbeat, stomach pain or Optic neuritis in some patients.

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