Generic Name: rosiglitazone

Brand Name:

Manufacturer: GlaxoSmithKline

Drug Functionality:

Indicated as a treatment, in conjunction with diet and exercise, for non-insulin dependent patients, Avandia is an oral medication taken one daily with or without food.  Belonging to a family of drugs called thiazolidinediones (TZD), Avandia increases the body’s sensitivity to insulin, a protein not adequately produced in diabetics, and helps control glucose (blood sugar).


Dosage should be followed as per the prescription and any alterations to the medication should be done only under medical supervision. Normally,

  • The dosage for patients suffering from Type 2 diabetes is 4, 6, or 8 mg once or twice a day. No additional benefits have been seen with more than 8 mg a day.
  • It should be taken at the same time each day.
  • Since it is meant to bring down the sugar levels in blood, constant blood sugar monitoring needs to be done.


Diabetic patients who also suffer from any of the following conditions should consult with the doctor before taking this medicine:

  • if you are allergic to rosiglitazone or any other medications
  • what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention any of the following: gemfibrozil (Lopid); other medications for diabetes; medications for high blood pressure, high cholesterol, heart failure, or prevention of heart attack or ; and rifampin (Rifadin, Rimactane, in Rifamate). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
  • if you have or have ever had any of the conditions mentioned in the IMPORTANT WARNING section or diabetic eye disease such as macular edema (swelling of the back of the eye) or liver disease.
  • if you have ever taken troglitazone (, no longer available in the United States), especially if you stopped taking it because you experienced side effects
  • if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking rosiglitazone, call your doctor.
  • if you have not yet experienced menopause (change of life; end of monthly menstrual periods) you should know that rosiglitazone may increase the chance that you will become pregnant even if you do not have regular monthly periods or you have a condition that prevents you from ovulating (releasing an egg from the ovaries). Talk to your doctor about methods of birth control that will work for you.

Side Effects: 

Common Side Effects:

  • Upper Respiratory Tract Infection
  • Back pain
  • Fatigue
  • Sinusitis
  • Diarrhea

Serious Side Effects:

If you are taking Avandia and experience any of the following side effects, contact your doctor or health provider immediately:

  • Edema, fluid accumulation and swelling of the limbs, hands, or feet
  • Unusual or sudden, rapid weight gain
  • Chest pain or discomfort
  • Trouble Breathing

Patients who have been prescribed Avandia should keep a check on the following:

1. Congestive

If you experience chest pain or discomfort or have trouble breathing it may be a sign of myocardial ischemic, the lack of blood flow to the body, or congestive heart failure, when the heart fails to function as an adequate pump. Contact your doctor of health care provider immediately if you experience any of these symptoms.

2. Macular Edema—

Blurred central vision, distorted vision, or vision that is tinted pink are all symptoms of macular edema, then blood vessels leak fluid into the retina.   If left untreated, macular edema can cause permanent vision damage or even blindness.

3. Edema—

Fluid trapped by the body’s tissues causes swelling in the limbs, hands, and feet and is the sign of a serious condition which can often lead to heart failure.  Edema needs immediate medical attention.

4. Hypoglycemia—

Diabetic patients can sometimes suffer from low blood sugar also known as hypoglycemia. The symptoms of this are headache, hunger, weakness, sweating, tremor, irritability, or trouble concentrating. This can be caused due to:

    1. Skipped meals
    2. Alcohol consumption
    3. or
    4. Long duration workouts.

5. Bone Fractures—

Women, more often then men, have reported bone fractures in arms, hands or feet while using Avandia. Frequent visits to doctor and undergoing regular medical check-ups are always recommended for diabetic patients.

Have you used Avandia and suffered a serious, life-threatening side effect?

Any individual or the relative of an individual who has suffered due to Avandia’s side effects is permitted to file a lawsuit.  Attorneys are available to help you determine whether you are qualified to seek compensation.  You may be eligible to seek reimbursement for medical expenses, compensation for pain and suffering, and punitive damages (compensation granted for losses suffered).

Different states have different legislation regarding medical lawsuits, so it is essential to hire an experienced and effective lawyer who can file the case. If you need further information about the harmful side effects of Avandia or legal advice concerning personal injury matters, we invite you to contact us or to fill out our form on this website for a free case evaluation.