High Rate of Failure was the main reason why DePuy Hip Implant systems were recalled. A study indicated that the five year failure of this product was approximately 13 % or 1 in 8 patients. The survey that was carried out by an independent national registry based in UK which is responsible for tracking implant performances and outcomes concluded that more patients with ASR Hip System implants than previously reported to had undergone revision surgery. In these revision surgeries, the existing hip implant was removed and was replaced with the new hip implant.

In ASR XL Total Hip Replacement a one piece metal component called acetabular cup was placed in the acetabulum. The femoral head was replaced with a metal ball that was connected to a metal stem placed inside the femur. The acetabular cup rested on and moved directly against the femoral head. This resulted in two metal parts rubbing against each other and producing friction. This friction allowed chromium and cobalt ions to escape and disperse to nearby parts of the body, in turn leading to elevated levels of cobalt and chromium ions in the bloodstream. These relocated ions also infiltrated the organs, produced local irritation, and even created cysts. Many cases were reported where doctors had to break open and leak the contents of these kinds of cysts while performing revision surgeries.

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