Cleviprex is a medicine given to improve blood circulation. It belongs to a group of drugs called calcium channel blockers. It is manufactured by The Medicines Company. It contains clevidipine butyrate as its main active ingredient. It is available as injections and used for treatment of hypertension or high blood pressure. It acts by relaxing or widening blood vessels and thus improves blood flow and reduces blood pressure.

Patients should be under regular monitoring of blood pressure and heart rate, while using this medicine. Patients should stick to recommended dosages and duration, as patients may feel fine but may need further treatment.  High blood pressure may sometimes show no symptoms, thus medication should be started or stopped only on consultation of a doctor. It should be accompanied with diet, exercises and other methods prescribed by the healthcare provider. Patients should keep it away from moisture, heat, and light and store it at room temperature.

Its overdose could be fatal. Overdose symptoms of this drug are slow heartbeats, severe dizziness, and fainting. Patients should avoid getting up too fast from a sitting or lying position, as this drug could cause dizziness in such conditions. They should get up slowly to prevent a fall. Patients allergic to clevidipine, eggs, or soy products, should not use this medicine.

Patients should tell doctor about their medical history to the doctor before having Cleviprex injections as it may worsen certain medical conditions. Patients with high cholesterol or triglyceride levels in blood, pancreatitis with high cholesterol or triglyceride, a kidney disorder such as lipoid nephrosis, or severe narrowing of the aortic valve in heart should not use this medicine or their condition may worsen.

Patients who are pregnant, planning to have a baby or mothers who are breast-feeding should not have this injection as it may harm the unborn or newborn child. If a patient has received Cleviprex injection ever, it is advisable to tell the doctor if the patient was pregnant afterwards. Patients using other medicines or having food allergies, pancreatitis, adrenal gland tumor or heart disease should tell their doctor about these conditions before having Cleviprex injection to be prevented from any severe side effect.

This injection could lead to allergic reactions and patients may suffer from hives, shortness of breath, swelling of face, lips, tongue, or throat. Some patients may also have feeling of passing out. Other serious side effects of this injection includes slow heart rate, stoppage or decrease in urination, drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea, vomiting, mild exertion, swelling, sudden weight gain, chest pain expanding up to the arm or shoulder, sweating or headache. Some patients may also suffer Hypotension as their blood pressure dips too low. There may be renal failure or hypoxemia in some patients too.