On January 31, 2010, the U.S. Food and Drug Administration (FDA) listed Actos, an oral medication prescribed to Type II diabetes patients who are not insulin dependent, in addition to various other drugs, on its watch list.  Actos, or pioglitazone, belongs in a class of medications called thiazolidinediones (TZDs). Manufactured by Takeda Pharmaceuticals, a subsidiary of the Japan’s largest drug company Takeda Pharmaceutical Company Limited, according to the FDA’s  Adverse Event Reporting System (AERS) with a reporting date of July-September 2010,  a safety risk was identified between Actos users and rhabdomyolysis, the release of muscle fibers into the bloodstream, a potentially fatal condition.

When muscles endure damage, through such events as muscle trauma or overuse, alcohol abuse, or drug use, they release a protein called myoglobin, an iron- and oxygen-binder found in the muscles of all vertebrates, into the bloodstream.  The kidneys then try and remove the myoglobin from the body through urine, but too much of this protein can cause severe kidney damage.  Because the course and location of rhabdomyolsis varies from patient to patient, symptoms are often difficult to pinpoint, but if you are using or have used Actos and experience abnormal urine color (dark, red, or cola-colored), decreased urine productions, muscle tenderness, weakness, or stiffness, or joint pain, contact your doctor immediately before severe damage occurs.  Urine tests can be performed in order to detect rhabdomyolsis.

Have You Been Affected by Actos?

Any individual or the relative of an individual who has suffered due to Actos’ side effects is permitted to file a lawsuit. We can put your case to lawyers to help you determine whether you are qualified to seek compensation. You may be eligible to seek reimbursement for medical expenses, compensation for pain and suffering, and punitive damages (compensation granted for losses suffered).  If you need further information about the harmful side effects of Actos or legal advice concerning personal injury matters, we invite you to contact us or to fill out our form on this website for a free case evaluation.